Many people wonder whether dark spots on the hands could be a sign of melanoma. The answer is: sometimes. While not all dark spots are dangerous, some may be early indicators of melanoma, a serious form of skin cancer. It’s important to know what signs to watch for and when to seek medical advice.
Melanoma originates in melanocytes—the cells that produce skin pigment. While it typically appears on areas like the back or legs, it can also develop on the hands, including the backs, palms (rarely), and even under the fingernails, a condition known as subungual melanoma.
To evaluate whether a dark spot might be melanoma, the ABCDE rule can be useful: Asymmetry (uneven halves), Border (irregular edges), Color (multiple or unusual shades), Diameter (larger than 6 mm), and Evolving (changes over time). Other warning signs include itching, bleeding, crusting, sudden appearance in adulthood, or a spot that looks very different from other moles
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