One of the first symptoms is muscle cramps or twitching. Magnesium helps muscles relax after contraction, so deficiency can cause painful night-time leg cramps, foot spasms, or eyelid twitches. Athletes and older adults are particularly vulnerable.
Chronic fatigue is another common sign. Magnesium is required to produce ATP, the energy molecule, so low levels can leave people feeling deeply tired, even after rest. Persistent exhaustion should raise concerns about magnesium status.
Sleep disturbances can occur because magnesium regulates neurotransmitters like GABA that promote relaxation. Low levels may cause difficulty falling asleep, frequent waking, or light, unrefreshing sleep. Poor sleep further depletes magnesium, creating a cycle that can be hard to break.
Emotional and cognitive issues may appear, including irritability, anxiety, difficulty concentrating, and mild depression. Magnesium helps regulate the nervous system, so deficiency can make stress harder to manage
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